Serum concentrations of IL-17A, IL-17B, IL-17E and IL-17F in patients with systemic sclerosis
نویسندگان
چکیده
منابع مشابه
Increased IL-17A but Decreased IL-27 Serum Levels in Patients with Multiple Sclerosis
Background: Effector CD4+ T cell subsets play an important role in Multiple Sclerosis (MS). Interleukin-27 (IL-27) suppresses Th (Th1, Th2 and Th17) cells and dampens autoimmunity and tissue inflammation by promoting the generation of Type 1 regulatory T cells (Tr1). Objective: To identify the relative levels of IL-27 and IL-17A in MS disease. Method: In a case-control study, venous blood was c...
متن کاملCorrelations between concentrations of interleukin (IL)-17A, IL-17B and IL-17F, and endothelial cells and proangiogenic cytokines in systemic lupus erythematosus patients.
Systemic lupus erythematosus (SLE) is an autoimmune disease of multifactorial pathoaetiology. Different organs and blood vessels may be affected by chronic inflammation. A direct cause of the disease has not yet been found, so research is being carried out to this effect. The role of the recently identified helper T lymphocyte CD4+, described as Th17, and its dependent cytokines have been of pa...
متن کاملInvestigating the Association of IL-17A and IL-17F with Susceptibility to Pre-eclampsia in Iranian Women
Background: Pre-eclampsia (PE) is one of the most important and life-threatening pregnancy disorders that affect at least 3-5% of all pregnancies. Imbalance in helper T cell functions may play a role in predisposing to PE or severity of the disease. Elevated frequencies of Th17 cells in the peripheral blood of PE patients have been reported. Several single nucleotide polymorphisms (SNP) within ...
متن کاملIdentification of cells expressing IL-17A and IL-17F in the lungs of patients with COPD.
BACKGROUND Lymphocytes secrete IL-17A and IL-17F, which enhance innate immune responses. IL-17 expression has not been studied in COPD small airways. The aim of this study was to quantify IL-17A and IL-17F expression in the peripheral lung tissue of patients with COPD compared with control subjects and to identify inflammatory cells that express IL-17. METHODS IL-17 expression was assessed us...
متن کاملincreased il-17a but decreased il-27 serum levels in patients with multiple sclerosis
background: effector cd4+ t cell subsets play an important role in multiple sclerosis (ms). interleukin-27 (il-27) suppresses th (th1, th2 and th17) cells and dampens autoimmunity and tissue inflammation by promoting the generation of type 1 regulatory t cells (tr1). objective: to identify the relative levels of il-27 and il-17a in ms disease. method: in a case-control study, venous blood was c...
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ژورنال
عنوان ژورنال: Archives of Medical Science
سال: 2019
ISSN: 1734-1922
DOI: 10.5114/aoms.2019.84738